XHANCE is the
FIRST and ONLY

FDA-approved medicine for adults with chronic rhinosinusitis without nasal polyps

Learn what makes
XHANCE different>

Learn More To Get Started >

Is XHANCE
right for me?

Fill out this short questionnaire to assess your symptoms. Use it to help you talk to your doctor about your symptoms.*

Check my symptoms >

How XHANCE
works

XHANCE uses your breath to deliver medicine high and deep into the nose to the source of the problem.

Watch Video >

How to
use XHANCE

XHANCE has a nosepiece and a flexible mouthpiece. This is different from traditional nasal sprays, but most people find it easy to use.^†

Watch the step-by-step video >

If your commercial health insurance covers XHANCE, your out-of-pocket cost could be as little as $0 using the XHANCE copay card

Eligible, commercially insured patients can pay
as little as $0 for their prescription of XHANCE.^‡

Download copay card >

Be sure to download or print your XHANCE
Copay Card to receive available savings.

^*This is not a diagnostic tool. Only your doctor can diagnose your condition. ^†In a follow-up survey of people who had taken XHANCE in clinical studies. ^‡These offers are not valid for use by cash-paying patients or patients enrolled in Medicare, Medicaid, and TRICARE or other federal or state programs. Offers are subject to quantity limitations. Maximum benefits per fill apply. Patient cost share may impact benefits and eligibility. Optinose^® reserves the right to rescind, revoke, or amend this offer without notice. Click here for additional terms and conditions.
If you have more questions about how to get and save on XHANCE, please see frequently asked questions about XHANCE support and savings.

Indications

XHANCE is a prescription medicine used to treat chronic rhinosinusitis with or without nasal polyps in adults. It is not known if XHANCE is safe and effective in children.

Important Safety Information

Do not use XHANCE if you are allergic to fluticasone propionate or any of the ingredients in XHANCE. Get emergency medical care if you get any of these signs of a serious allergic reaction: rash, hives, swelling of your face, mouth, and tongue, breathing problems, or low blood pressure.
XHANCE can cause nasal problems such as nosebleeds, crusting, sores, hole in the septum, and slow wound healing. You should not use XHANCE until your nose has healed if you have a sore on your nose, have had surgery on your nose, or if your nose is injured.
XHANCE can cause eye problems including glaucoma and cataracts. You should have regular eye exams when using XHANCE. Call your doctor if you have vision changes while using XHANCE.
XHANCE may increase the risk of infections and can make certain infections worse. Avoid contact with people who have a contagious disease such as chickenpox or measles while using XHANCE.
XHANCE can cause reduced production of steroid hormones by your adrenal gland, resulting in tiredness, weakness, nausea and vomiting, and low blood pressure.
XHANCE can weaken bones (osteoporosis).
The most common side effects include: nose bleeds, sores (ulcers) in your nose, pain or swelling of your nose or throat, redness in your nose, nasal congestion, sinus infection and headache.
Tell your healthcare provider about all your medical conditions and medications that you take. It is especially important to mention if you take antifungal or anti-HIV medicines as they may interact with XHANCE.

These are not all the side effects of XHANCE. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Patient Information, full Prescribing Information and Instructions for Use.

XHANCE is theFIRST and ONLY

Is XHANCE right for me?

How XHANCE works

How touse XHANCE